ea0003oc45 | Neuroendocrinology | BES2002
Epton M
, Chapman L
, Morris J
, Buckingham J
, Christian H
Annexin I (ANXA1), a Ca2+- and phospholipid-binding protein is an important mediator of glucocorticoid (GC) action in the host defence and neuroendocrine systems. In the anterior pituitary ANXA1 is highly expressed by the folliculo-stellate (FS) cells (1). We have shown that GCs cause the externalization of annexin I in a FS cell line (murine TtT/GF) despite the fact that ANXA1 lacks a signal sequence and is not packaged in secretory granules. In bacteria and yeast ...